Dextran 40

Clinical grade Dextran 40 is available from Pharmacosmos as Active Pharmaceutical Ingredients (API) for production of solutions for injection and infusion.

Specifications for Dextran 40

Pharmacosmos supplies Dextran 40 complying with any pharmacopoeial requirements, including:

Product	Normative Mw	Specification
Dextran 40	40,000 Da	Ph. Eur.
Dextran 40	40,000 Da	USP
Dextran 40	40,000 Da	JP

Please contact us for information about other specifications.

Documentation for Dextran 40

Pharmacosmos is the only Dextran manufacturer that has received the certificate from the European Directorate for the Quality of Medicines (EDQM) for the specific pharmacopoeial Dextran 40 clinical grade.

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Dextran 40 Monograph

For additional information about the Dextran 40, Ph.Eur. Monograph, please visit EDQM's website:

Dextran 40, Ph. Eur., Monograph Details
(EDQM Monograph No.: 999)

Packing and Storage of Clinical Dextrans

Clinical grade Dextrans from Pharmacosmos are packed and stored in safe and clean conditions in compliance with Good Manufacturing Practice (GMP).

Clinical grade Dextran 40 is available in the following pack sizes:

Pack Size	Remarks
100 g	Polyethylene container, FDA registrered, DMF type III
500 g	Polyethylene container, FDA registrered, DMF type III
5 kg	Polypropylene container. Dextran powder sealed in double polyethylene bags.
50 kg	Fiber drums. Dextran powder sealed in double polyethylene bags.

Pharmacosmos supplies clinical grade Dextrans to all countries. The product packing meets all national and international regulations.

Clinical Use of Dextran 40

Plasma Expander

Both clinical grade Dextran 40 and Dextran 70 have been marketed in the US for several years. Dextran 40 and Dextran 70 intravenous solutions are approved by the US Food & Drug Administration (FDA) for plasma volume expansion in the treatment of hypovolemic shock and as a component of the pump prime for cardiopulmonary bypass.

Dextran 40 in Rheomacrodex®

Dextran 40 for injection is an Active Pharmaceutical Ingredient (API) in Rheomacrodex® used for prophylaxis of postoperative and post-traumatic thromboembolism. Rheomacrodex® may also be used as plasma volume replacement.